Everywhere N is up and W is right.
Below: M99 (16", 225x)
Below: M100 with NGC 4322, -3, and -8 (16", 225x)
Below: M104 (16", 45 and 225x, some features are illusory)
Below: NGC 253 (12" SCT, 125 and 230x)
Below: NGC 3184 with star clouds NGC 3180 and 3181 (12" SCT, 230x)